Agents are the characters in Agents of Mayhem players may choose to play as.
- Players start the game by selecting a team of three different agents.
- While playing, agents can be swapped on the fly with the push of a button.
- While agents are swapped out, they regenerate health.
- Agents each have their own weapon, ability, and Mayhem ability.
- Agents can be customized with different gadgets and skins.